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Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Set_01_ATM_minus_versus_SCID.phenotype_ATM_minus_versus_SCID.cls #ATM_minus_versus_SCID |
| Phenotype | phenotype_ATM_minus_versus_SCID.cls#ATM_minus_versus_SCID |
| Upregulated in class | SCID |
| GeneSet | INOH_T CELL RECEPTOR SIGNALING (PLC GAMMA, PKC, RAS AND IKK-NF-KAPPAB CASCADE) |
| Enrichment Score (ES) | -0.6531723 |
| Normalized Enrichment Score (NES) | -1.5228158 |
| Nominal p-value | 0.039583333 |
| FDR q-value | 0.87789357 |
| FWER p-Value | 1.0 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | PTK2B | 1434653_at 1442437_at 1442927_at | 157 | 2.473 | 0.0924 | No | ||
| 2 | JAK1 | 1433803_at 1433804_at 1433805_at | 614 | 1.251 | 0.1220 | No | ||
| 3 | NFKBIE | 1431843_a_at 1458299_s_at | 1470 | 0.626 | 0.1082 | No | ||
| 4 | PRKCQ | 1426044_a_at | 2083 | 0.447 | 0.0983 | No | ||
| 5 | ITPR1 | 1417279_at 1443492_at 1457189_at 1460203_at | 3020 | 0.296 | 0.0675 | No | ||
| 6 | SYK | 1418261_at 1418262_at 1425797_a_at 1457239_at | 3700 | 0.234 | 0.0459 | No | ||
| 7 | LCK | 1425396_a_at 1439145_at 1439146_s_at 1457917_at | 4705 | 0.172 | 0.0070 | No | ||
| 8 | FYN | 1417558_at 1441647_at 1448765_at | 5640 | 0.133 | -0.0303 | No | ||
| 9 | NFKBIA | 1420088_at 1420089_at 1438157_s_at 1448306_at 1449731_s_at | 6463 | 0.107 | -0.0635 | No | ||
| 10 | BTK | 1422755_at | 6790 | 0.098 | -0.0744 | No | ||
| 11 | TEC | 1441524_at 1460204_at | 6821 | 0.097 | -0.0719 | No | ||
| 12 | SRC | 1423240_at 1450918_s_at | 7866 | 0.070 | -0.1167 | No | ||
| 13 | LAT | 1460651_at | 8892 | 0.047 | -0.1616 | No | ||
| 14 | ZAP70 | 1422701_at 1439749_at 1440178_x_at | 9455 | 0.035 | -0.1859 | No | ||
| 15 | PLCG1 | 1435149_at 1450360_at | 18539 | -0.259 | -0.5900 | No | ||
| 16 | RELA | 1419536_a_at | 18783 | -0.282 | -0.5897 | No | ||
| 17 | JAK2 | 1421065_at 1421066_at | 18962 | -0.299 | -0.5858 | No | ||
| 18 | ITPR3 | 1417297_at | 20439 | -0.595 | -0.6292 | Yes | ||
| 19 | TYK2 | 1417306_at | 20592 | -0.646 | -0.6101 | Yes | ||
| 20 | CD4 | 1419696_at 1427779_a_at | 21313 | -1.221 | -0.5938 | Yes | ||
| 21 | NFKB1 | 1427705_a_at 1442949_at | 21538 | -1.611 | -0.5392 | Yes | ||
| 22 | PTK2 | 1423059_at 1430827_a_at 1439198_at 1440082_at 1441475_at 1443384_at 1445137_at | 21633 | -1.852 | -0.4689 | Yes | ||
| 23 | JAK3 | 1425750_a_at 1446515_at | 21731 | -2.244 | -0.3830 | Yes | ||
| 24 | NFKBIB | 1421266_s_at 1446718_at | 21782 | -2.588 | -0.2810 | Yes | ||
| 25 | ITK | 1417171_at 1430833_at 1452518_a_at 1456836_at 1457120_at | 21862 | -3.312 | -0.1513 | Yes | ||
| 26 | CSK | 1423518_at 1439744_at | 21885 | -3.839 | 0.0023 | Yes |
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